What Is Curcumin?
Curcumin is a naturally occurring polyphenol found in the rhizome, or underground stem, of Curcuma longa. This is the plant commonly known as turmeric.
Cell studies examine how curcumin influences NF-κB signalling, which helps regulate inflammatory gene expression. Researchers assess these effects in specific cell types and experimental conditions.
These findings inform its selection for NovaStemix®. We consider curcumin’s research profile alongside its ingredient form, specification and daily amount within the complete 12-ingredient formula.
Ingredient Form &
Specification
NovaStemix® uses a liposomal curcumin preparation. Its raw material specification describes the curcumin content, liposome size and encapsulation characteristics.
We consider the preparation’s composition, specification and daily amount alongside the other ingredients in the complete 12-ingredient formula.
The Science Behind
Cellular Mechanisms
Cell experiments investigate how curcumin affects NF-κB activation and inflammatory gene expression. Researchers examine IκBα regulation and the movement of NF-κB components into the nucleus under defined laboratory conditions.
Human Research
An eight-week randomised trial in 117 adults with metabolic syndrome reported lower C-reactive protein with curcuminoids plus piperine than with placebo. These findings concern a specific preparation and population.
Formulation Context
Preparation, dose, study duration and participant characteristics matter when interpreting findings. We consider these factors alongside the liposomal curcumin ingredient’s specification and daily amount within the complete NovaStemix® formula.
Why It Is Included in NovaStemix®
We include curcumin in NovaStemix® for its research profile in inflammatory signalling. Cell studies examine how it influences NF-κB activation and the expression of genes involved in inflammatory responses.
Resveratrol is studied for its effects on metabolic signalling, while NR is a precursor to NAD⁺. We consider these distinct roles and research areas together when designing the complete formula.
NovaStemix® uses a liposomal curcumin preparation. We consider its form, specification and daily amount alongside the other ingredients within the complete 12-ingredient formula.
Research Areas
Selected areas of experimental curcumin research that inform our formulation approach.
EXPERIMENTAL RESEARCH
Inflammatory Signalling
EXPERIMENTAL RESEARCH
Antioxidant Responses
EXPERIMENTAL RESEARCH
Cellular Stress Responses
EXPERIMENTAL RESEARCH
Autophagy Regulation
Related Ingredients
RESVERATROL
PQQ
NR
Resveratrol is studied for its effects on metabolic signalling and mitochondrial function in experimental models. These research areas inform its inclusion within the complete NovaStemix® formula.
PQQ is studied in cell models for its effects on mitochondrial biogenesis, the formation of new mitochondria. This experimental research informs its inclusion within the complete NovaStemix® formula.
NR is a precursor to NAD⁺, a coenzyme involved in cellular energy metabolism. Human studies have observed increases in blood NAD⁺ after supplementation with specific NR preparations.