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PLANT POLYPHENOL · CELLULAR RESEARCH

Resveratrol

Resveratrol is a plant polyphenol studied in relation to Sirtuin signalling, mitochondrial function and energy metabolism.

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These research areas inform its inclusion in NovaStemix® as part of our 12-ingredient approach to healthy ageing.

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What Is Resveratrol?

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Resveratrol is a naturally occurring plant polyphenol found in grape skins and other plant sources. It belongs to the stilbene family and is produced by plants as part of their response to environmental stress.

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Researchers have studied how resveratrol influences cellular signalling, including SIRT1- and AMPK-related pathways involved in energy metabolism and stress responses.

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This work spans laboratory experiments and human studies examining selected metabolic outcomes. It provides a scientific background for understanding resveratrol’s place in healthy ageing nutrition.

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Natural Origins & Ingredient Form

Resveratrol occurs naturally in grapes and several other plants. In plants, its production can increase in response to environmental stresses, including ultraviolet exposure and microbial challenge.

NovaStemix® uses a liposomal resveratrol preparation.

 

We consider the ingredient’s form, specification and daily amount as part of the complete 12-ingredient formulation.

Scientific Context

Cellular Mechanisms

Laboratory and animal studies investigate resveratrol’s effects on SIRT1- and AMPK-related signalling, energy sensing and mitochondrial function. These findings provide mechanistic context for healthy ageing research.

Human Research

Human trials have examined mitochondrial function, insulin sensitivity and other metabolic markers. Findings differ across study populations and protocols, highlighting the importance of dose, duration and the outcomes measured.

Complementary Design

NR is a precursor to NAD⁺, a molecule required for sirtuin enzyme activity. This biological relationship helps explain why NR and resveratrol are considered together in NovaStemix®’s formulation design.

Why It Is Included in NovaStemix®

Resveratrol is included in NovaStemix® for its research links with cellular stress responses, metabolic signalling and mitochondrial function. These areas inform its place within a formula designed around cellular energy, maintenance and protection.

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NovaStemix® uses a liposomal resveratrol preparation. The recommended daily portion of four capsules provides 150 mg of trans-resveratrol.

Selected pathways explored in experimental resveratrol research, informing the biological rationale for its inclusion in NovaStemix®.

Cellular Stress Responses
Cell studies examine Nrf2-related signalling and the expression of cellular defence enzymes.

Pathway Mapping

Mitochondrial Function
Research explores SIRT1, AMPK and their links with mitochondrial function and energy metabolism.
Autophagy & Maintenance
Experimental studies investigate autophagy and the breakdown and recycling of cellular components.
Inflammatory Signalling
Cell studies examine NF-κB signalling and the expression of inflammation-related genes.

Related Ingredients

NR

NR is a precursor to NAD⁺, a coenzyme involved in cellular energy metabolism. It is included alongside resveratrol as part of the formula’s focus on energy and cellular regulation.

Quercetin

A plant flavonoid studied for its effects on NF-κB and MAPK signalling in cell models. Its research profile informs the formula’s focus on cellular stress responses and inflammatory signalling.

PQQ

Cell studies link PQQ with PGC-1α-related signalling and mitochondrial biogenesis. This research provides a mechanistic rationale for its inclusion in the wider NovaStemix® formula.

Continue Exploring the Formula

Explore the full NovaStemix® formula to learn more about all 12 ingredients, or visit the product page for recommended use, suitability and ordering information.

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