What Is PQQ?
PQQ stands for pyrroloquinoline quinone. It is a redox-active compound, meaning it can participate in reactions involving the transfer of electrons.
Cell studies examine how PQQ affects CREB and PGC-1α, regulators involved in the formation of new mitochondria. Researchers measure changes in mitochondrial content and cellular respiration.
These experimental findings explain the interest in PQQ within healthy ageing research and inform its selection for the NovaStemix® formula.
Ingredient Form & Specification
NovaStemix® uses a microencapsulated preparation of PQQ disodium salt. Its raw material specification describes the PQQ content and preparation characteristics.
We consider the ingredient’s form, specification and daily amount alongside the other components of the complete 12-ingredient formula.
The Science Behind PQQ
Cellular Mechanisms
Experiments in mouse cells reported increases in mitochondrial content and oxygen consumption after PQQ exposure. The research examined CREB and PGC-1α, regulators involved in mitochondrial biogenesis.
Human Research
A study in 10 adults reported reductions in selected inflammatory markers and changes in urinary metabolites after PQQ supplementation. These exploratory findings provide context for further human research.
Formulation Context
Preparation, dose, study duration and the outcomes measured matter when interpreting findings. We consider these details alongside the PQQ ingredient’s form and daily amount within the complete NovaStemix® formula.
Why It Is Included in NovaStemix®
Experimental research on PQQ examines mitochondrial biogenesis and cellular respiration, including mechanisms involving CREB and PGC-1α. These findings inform its selection for NovaStemix®.
NR is a precursor to NAD⁺, while coenzyme Q10 participates in mitochondrial electron transport. We consider these roles alongside PQQ’s research profile when designing the complete formula.
NovaStemix® uses a microencapsulated PQQ disodium preparation. Its form, specification and daily amount are considered within the complete 12-ingredient formula.
Research Areas
Selected areas of experimental PQQ research that inform our formulation approach.
EXPERIMENTAL RESEARCH
Mitochondrial Biogenesis
EXPERIMENTAL RESEARCH
Cellular Respiration
EXPERIMENTAL RESEARCH
Redox Activity
EXPERIMENTAL RESEARCH
